TAKE ACTION. Your patient meets criteria for an increased risk of hereditary cancer based on an identified mutation.
Your response to the initial assessment indicates that your patient has an increased risk based on a specific gene identified via tumor profiling and/or a blood relative with a known mutation in a cancer susceptibility gene. Your patient should be referred for genetic counseling and possible genetic testing for the specific mutation. Below are some resources for you and your patient.
- Download fact sheet about risk for a known cancer predisposition gene.
- Download fact sheet about hereditary cancer.
Different hereditary cancer conditions cause increased risks in specific cancers. The most common syndromes are:
- Hereditary breast and ovarian cancer (HBOC) syndrome (increased risk for breast (male and female), ovarian, endometrial, and metastatic prostate cancer). Download HBOC fact sheet.
- Lynch syndrome (increased risk for colorectal and endometrial cancer). Download Lynch syndrome fact sheet.
- Hereditary polyposis syndromes (increased risk for colorectal cancer). Download hereditary polyposis fact sheet.
Other less-common syndromes are Li-Fraumeni Syndrome, Cowden Syndrome, Von Hippel Lindau (VHL), and Multiple Endocrine Neoplasia (MEN). Download fact sheet for less-common hereditary cancer conditions.
If you have questions or concerns about your patient’s personal or family medical history of cancer, contact a cancer genetics provider.
- Directory of cancer genetics professionals in Michigan:
MCGA Directory of Cancer Genetic Services Providers
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